A man has been shot during a frightening break-in at a business in Beenleigh.

A group of offenders tried to break into the business on Logan River Rd just before 10pm on Thursday.

However, they were interrupted by a man and a woman at the business.

The man has then been shot in the leg before the offenders fled the scene on foot.

The 51-year-old was later taken to the Princess Alexandra Hospital in Brisbane with non-life-threatening injuries.

The 51-year-old woman was uninjured.

Police have set up a crime scene at the business while the hunt continues for the offenders.

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Detectives are appealing for any witnesses or anyone with relevant CCTV or dashcam footage to contact them.

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